Wuhan HengHeDa Pharm Co., Ltd.

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Profile: Wuhan HengHeDa Pharm Co., Ltd. offers fine chemicals, active pharmaceutical ingredients and pharmaceutical intermediates. Our fine chemicals include trans-3-hydroxy-L-proline, 2-methyl-D-proline, 2-methyl-L-proline, cis-4-hydroxy-L-proline, 1,2-dideoxy-4,5-O-(1-methylethylidene)-D-threo-pent-1-enito, 3-(4-chlorobutyl)-1H-indole-5-carbonitrile and (2S,3S)-3-hydroxy-1,2-pyrrolidinedicarboxylic acid, and 1-(phenyl methyl) ester. Our active pharmaceutical ingredients include 5-(1-piperazinyl)-2-benzofurancarboxylic acid ethyl ester hydrochloride, ethyl 5-amino-1-benzofuran-2-carboxylate, 3-(4-chlorobutyl)-1H-indole-5-carbonitrile, 5-(piperazin-1-yl)benzofuran-2-carboxamide, ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate, carmoterol hydrochloride and vilazodone HCl.

21 Products/Chemicals (Click for related suppliers)

• a-Methyl-L-proline

IUPAC Name: 2-methylpyrrolidine-2-carboxylic acid | CAS Registry Number: 42856-71-3
Synonyms: 2-Methylproline, alpha-Methylproline, L-Proline, 2-methyl-, NSC14964, NSC 14964, 2-Methyl-pyrrolidine-2-carboxylic acid

Molecular Formula:	C₆H₁₁NO₂	Molecular Weight:	129.157040 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	3

InChIKey: LWHHAVWYGIBIEU-UHFFFAOYSA-N

• Active Pharmaceutical Ingredient (API)

• Carmoterol

IUPAC Name: 8-hydroxy-5-[(1R)-1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one | CAS Registry Number: 147568-66-9
Synonyms: CHF 4226, CID6093400, 8-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one, 2(1H)-Quinolinone, 8-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)-, (R-(R*,R*))-

Molecular Formula:	C₂₁H₂₄N₂O₄	Molecular Weight:	368.426260 [g/mol]
H-Bond Donor:	4	H-Bond Acceptor:	5

InChIKey: IHOXNOQMRZISPV-YFKXAPIDSA-N

• Carmoterol Intermediate

IUPAC Name: 5-acetyl-8-phenylmethoxy-1H-quinolin-2-one | CAS Registry Number: 93609-84-8
Synonyms: 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one, 2(1H)-Quinolinone, 5-acetyl-8-(phenylmethoxy)-, ACMC-20aaf2, SureCN98338, acetylbenzyloxydihydroquinolinone, CTK3G9552, MolPort-020-313-360, ANW-64428, AKOS015991346, MCULE-8019757148, RP15870, AK103843, KB-88240, 5-acetyl-8-(benzyloxy)-1H-quinolin-2-one, 5-Acetyl-8-(benzyloxy)-1,2-dihydro-2-oxoquinoline, 1-[8-(Benzyloxy)-1,2-dihydro-2-oxoquinolin-5-yl]ethan-1-one

Molecular Formula:	C₁₈H₁₅NO₃	Molecular Weight:	293.316600 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	3

InChIKey: MVYPGJMOODJFAZ-UHFFFAOYSA-N

• Custom Fine Chemicals

• D-proline, 2-methyl

IUPAC Name: (2R)-2-methylpyrrolidine-2-carboxylic acid | CAS Registry Number: 63399-77-9
Synonyms: (R)-2-Methylproline, AmbtgM80025, MolPort-001-770-206, M80025

Molecular Formula:	C₆H₁₁NO₂	Molecular Weight:	129.157040 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	3

InChIKey: LWHHAVWYGIBIEU-ZCFIWIBFSA-N

• Ethyl 5-(Piperazin-1-Yl)Benzofuran-2-Carboxylate

IUPAC Name: ethyl 5-piperazin-1-yl-1-benzofuran-2-carboxylate | CAS Registry Number: 163521-20-8
Synonyms: Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate, AGN-PC-005MBW, SureCN1888638, CTK8C1087, MolPort-021-784-834, ANW-65858, AKOS015924745, AK-87461, KB-77148, ethyl 5-piperazin-1-yl-1-benzofuran-2-carboxylate

Molecular Formula:	C₁₅H₁₈N₂O₃	Molecular Weight:	274.315020 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	5

InChIKey: ZKLDXJIVWKPASZ-UHFFFAOYSA-N

• Fine Chemicals

• Herbal Extracts

• Indacaterol Maleic Acid Salt

IUPAC Name: (Z)-but-2-enedioic acid;5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one | CAS Registry Number: 753498-25-8
Synonyms: Indacaterol maleate, Arcapta Neohaler, UNII-2JEC1ITX7R, CHEBI:68573, Oslif Breezhaler, Onbrez Breezhaler, Hirobriz Breezhaler, QAB-149 maleate, Arcapta neohaler (TN), 2JEC1ITX7R, Onbrez Inhalation Capsules, SureCN523627, QAB149-AFA, QAB-149-AFA, CHEMBL1789842, Indacaterol maleate (JAN/USAN), D09319, 5,6-diethyl-N-[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl]indan-2-aminium (2Z)-3-carboxyacrylate, 5-{(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl}-8-hydroxyquinolin-2(1H)-one (2Z)-but-2-enedioate

Molecular Formula:	C₂₈H₃₂N₂O₇	Molecular Weight:	508.562880 [g/mol]
H-Bond Donor:	6	H-Bond Acceptor:	8

InChIKey: IREJFXIHXRZFER-PCBAQXHCSA-N

• L-3-Trans-Hydroxyproline

IUPAC Name: (2S,3S)-3-hydroxypyrrolidin-1-ium-2-carboxylate | CAS Registry Number: 4298-08-2
Synonyms: trans-L-3-Hydroxyproline, CPD-664, ZINC04096639, CID11877126

Molecular Formula:	C₅H₉NO₃	Molecular Weight:	131.129860 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	3

InChIKey: BJBUEDPLEOHJGE-IMJSIDKUSA-N

• Sodium Valproate

IUPAC Name: sodium 2-propylpentanoate | CAS Registry Number: 1069-66-5
Synonyms: Sodium valproate, Valproate sodium, Depakene, Epilim, Convulex, Eurekene, Labazene, Orfiril, Valerin, Natrium valproat, Selenica, Sodium 2-propylpentanoate, Valproic acid sodium salt, Dipropylacetate sodium, Sodium dipropylacetate, Depakene (TN), Selenica (TN), Sodium bispropylacetate, Valproic acid sodium, Valproinsaeure, natrium

Molecular Formula:	C₈H₁₅NaO₂	Molecular Weight:	166.193270 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	2

InChIKey: AEQFSUDEHCCHBT-UHFFFAOYSA-M

• Vilazodone

IUPAC Name: 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide | CAS Registry Number: 163521-12-8
Synonyms: Vilazodone [INN], CHEBI:412971, CID6918314, L001518, 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide, 5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide

Molecular Formula:	C₂₆H₂₇N₅O₂	Molecular Weight:	441.524880 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	5

InChIKey: SGEGOXDYSFKCPT-UHFFFAOYSA-N

• 8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline

IUPAC Name: 5-(2-bromoacetyl)-8-phenylmethoxy-1H-quinolin-2-one | CAS Registry Number: 100331-89-3
Synonyms: 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline, 8-Benzyloxy-5-(2-Bromoacetyl)-1H-quinolin-2-one, 1-(8-(benzyloxy)-2-hydroxyquinolin-5-yl)-2-bromoethanone, 2(1H)-Quinolinone,5-(2-bromoacetyl)-8-(phenylmethoxy)-, PubChem13456, ACMC-209y3a, CTK3J8799, MolPort-009-198-427, ACT04908, 5-Bromoacetyl-8-benzyloxycarbostyril, 8-Benzyloxy-5-bromoacetylcarbostyril, ANW-48452, ZINC15442646, AKOS015920361, AG-D-05135, RL00032, AK-28344, BR-28344, KB-46651, KB-250227

Molecular Formula:	C₁₈H₁₄BrNO₃	Molecular Weight:	372.212660 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	3

InChIKey: RVHSDLUBNZBRMH-UHFFFAOYSA-N

• 1,4-Benzenediamine, N1,N1,N4,N4-tetrakis[4-(dibutylamino)phenyl]-

IUPAC Name: 1-N,1-N-dibutyl-4-N-[4-[4-(dibutylamino)-N-[4-(dibutylamino)phenyl]anilino]phenyl]-4-N-[4-(dibutylamino)phenyl]benzene-1,4-diamine | CAS Registry Number: 4182-80-3
Synonyms: EINECS 224-057-8, 1,4-Benzenediamine, N,N,N',N'-tetrakis(4-(dibutylamino)phenyl)-, N,N,N',N'-Tetrakis(4-(dibutylamino)phenyl)-1,4-benzenediamine, N,N,N',N'-Tetrakis(4-(dibutylamino)phenyl)benzene-1,4-diamine, 171903-72-3

Molecular Formula:	C₆₂H₉₂N₆	Molecular Weight:	921.434080 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	6

InChIKey: GVNSFLFOZIYBPH-UHFFFAOYSA-N

• 8-Benzyloxy-5-((R)-2-bromo-1-hydroxyethyl)-1H-quinolinone

IUPAC Name: 5-[(1R)-2-bromo-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one | CAS Registry Number: 530084-79-8
Synonyms: (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one, SureCN99134, CTK8B6406, ANW-53407, AKOS015999468, AK-93364, BD230882, KB-210249, (R)-8-Benzyloxy-5-(2-bromo-1-hydroxyethyl)carbostyril, 5-(2-Bromo-(R)-1-hydroxyethyl)-8-benzyloxy-2(1H)-quinolinone, 8-(Benzyloxy)-5-((1R)-2-bromo-1-hydroxyethyl)quinolin-2(1H)-one, 5-[(1R)-2-Bromo-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone

Molecular Formula:	C₁₈H₁₆BrNO₃	Molecular Weight:	374.228540 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	3

InChIKey: GNFMSZCSSUZAGV-HNNXBMFYSA-N

• 5-(piperazin-1-yl)benzofuran-2-carboxamide

IUPAC Name: 5-piperazin-1-yl-1-benzofuran-2-carboxamide | CAS Registry Number: 183288-46-2
Synonyms: 5-(Piperazin-1-yl)benzofuran-2-carboxamide, 1-(2-Aminocarbonylbenzofuran-5-yl)piperazine, 2-Benzofurancarboxamide, 5-(1-piperazinyl)-, SureCN1322886, BEN783, CTK8B4376, ANW-44872, AKOS015998995, RL02335, AK-82278, BD227885, KB-73076, AM20120671, X3185

Molecular Formula:	C₁₃H₁₅N₃O₂	Molecular Weight:	245.277100 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	4

InChIKey: LLRGOAFFRRUFBM-UHFFFAOYSA-N

• 2-BENZOFURANCARBOXYLIC ACID 5-AMINO-,ETHYL ESTER

IUPAC Name: ethyl 5-amino-1-benzofuran-2-carboxylate | CAS Registry Number: 174775-48-5
Synonyms: Ethyl 5-Amino-1-benzofuran-2-carboxylate, Ethyl 5-aminobenzofuran-2-carboxylate, SBB053980, 5-Amino-2-(ethoxycarbonyl)-1-benzofuran, Ethyl 5-aminobenzo[b]furan-2-carboxylate, ethyl 5-aminobenzo[d]furan-2-carboxylate, PubChem23808, SureCN2255398, ethylaminobenzofurancarboxylate, KSC494O5F, CTK3J4752, MolPort-001-770-435, ANW-45651, WT2071, ZINC12336529, AKOS005072009, AG-B-21781, AM84613, LS40931, MCULE-2406800244

Molecular Formula:	C₁₁H₁₁NO₃	Molecular Weight:	205.209940 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	4

InChIKey: YFFLLDHEEWSHQG-UHFFFAOYSA-N

• 3-(4-CHLORBUTYL)-1H-INDOL-5-CARBONITRIL

IUPAC Name: 3-(4-chlorobutyl)-1H-indole-5-carbonitrile | CAS Registry Number: 143612-79-7
Synonyms: 3-(4-chlorobutyl)-1H-indole-5-carbonitrile, 3-(4-Chlorbutyl)-1H-indol-5-carbonitril, SureCN3082624, CTK8B4377, MolPort-005-933-361, ANW-44873, CL3519, WTI-11918, ZINC22010755, AKOS015924756, LS20798, QC-1507, RP28041, AK-79876, BD227883, KB-69845, WT-130087, AM20020489, X6201, I10-1537

Molecular Formula:	C₁₃H₁₃ClN₂	Molecular Weight:	232.708720 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	1

InChIKey: NJJWMEJWFYRORL-UHFFFAOYSA-N

• 8-HYDROXY-5-(1-HYDROXY-2-(N-(2-(4-METHOXYPHENYL)-ISOPROPYL)AMINO)ETHYL)CARBOSTYRIL HCL

IUPAC Name: 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]-1H-quinolin-2-one hydrochloride | CAS Registry Number: 137888-11-0
Synonyms: Carmoterol hydrochloride, CHF-4226, CID63951, TA-2005, TA 2005, CHF 4226.01, LS-142795, 2(1H)-Quinolinone, 8-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)-, hydrochloride, (R-(R*,R*))-, 8-Hydroxy-5-((1R)-1-hydroxy-2-(N-(1R)-2-(p-methoxyphenyl)isopropylamino)ethyl)carbostyril HCl, 100429-08-1, 2(1H)-Quinolinone, 8-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)-, monohydrochloride, (R-(R*,R*))-, 8-Hydroxy-5-(1-hydroxy-2-(N-(2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)carbostyril hydrochloride

Molecular Formula:	C₂₁H₂₅ClN₂O₄	Molecular Weight:	404.887200 [g/mol]
H-Bond Donor:	5	H-Bond Acceptor:	5

InChIKey: SYCWERNQGSKYAG-QVRIGTRMSA-N

• (R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)quinolin-2(1H)-one

IUPAC Name: 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one | CAS Registry Number: 435273-75-9
Synonyms: SureCN1221324, AKOS015999461, AK-93361, (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one

Molecular Formula:	C₃₁H₃₄N₂O₃	Molecular Weight:	482.613260 [g/mol]
H-Bond Donor:	3	H-Bond Acceptor:	4

InChIKey: OTINTMLHLKCOBW-NDEPHWFRSA-N