PRODUCT NAME | CAS Registry Number | ||||||||
5-[4-morpholin-4-yl-6-(propan-2-ylsulfanylmethyl)pyrimidin-2-yl]-1H-indole (0 suppliers) | 944059-06-7 | ||||||||
5-[4-Nitro-2-(trifluoromethyl)phenyl]-2H-1,2,3,4-tetraazole (1 supplier) | |||||||||
5-[4-nitro-2-(trifluoromethyl)phenyl]-2H-1,2,3,4-tetrazole (2 suppliers)![]() Synonyms: 5-[4-nitro-2-(trifluoromethyl)phenyl]-2H-1,2,3,4-tetraazole, 5-[4-nitro-2-(trifluoromethyl)phenyl]-2H-tetrazole, 5-(4-Nitro-2-(trifluoromethyl)phenyl)-2H-tetrazole, MFCD13193117, ZINC40566717, AKOS005073392, LD-0050
InChIKey: PQSIDAYQUUYIKI-UHFFFAOYSA-N | 1192263-78-7 | ||||||||
5-[4-Nitro-3-(trifluoromethyl)phenyl]-2H-1,2,3,4-tetraazole (2 suppliers) | |||||||||
5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-(p-tolyl)-1,2,4-oxadiazole (3 suppliers)![]() Synonyms: ZINC02143795, AC1MCBHN, MolPort-002-921-025, AK136753, KB-41416, 3-(4-methylphenyl)-5-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-1,2,4-oxadiazole, 3-(4-methylphenyl)-5-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]-1,2,4-oxadiazole
InChIKey: MFHDEQCWZMUWPL-UHFFFAOYSA-N | 256414-84-3 | ||||||||
5-[4-Phenyl-5-(trifluoromethyl)-2-Thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-Oxadiazole (11 suppliers)![]() Synonyms: SEW2871, SEW-2871, S1P1 Receptor Agonist, SEW2871, Sphingosine-1-Phosphate1 Receptor S1P1 Agonist, 5-(4-Phenyl-5-trifluoromethylthiophen-2-yl)-3-(3-trifluoromethylphenyl)-(1,2,4)-oxadiazole, 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole, 5-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole, 5-(4-Phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole, AC1N2UY4, S3944_SIGMA, CHEMBL224720, GTPL2926, CTK7B7082, CHEBI:474115, MolPort-000-146-354, HMS3268H16, SEW 2871, SEW02871, IN1083, ZINC02141876
InChIKey: OYMNPJXKQVTQTR-UHFFFAOYSA-N | 256414-75-2 | ||||||||
5-[4-PYRIDYL]-1H-1,2,3,4-TETRAZOLE (1 supplier) | |||||||||
5-[4[[2-Butyl-4-chloro-5-[[(1-methyl)oxy]methyl-1H-imidazol-1-yl]-methyl-biphenyl-2-yl]-1H-tetrazole (0 suppliers) | |||||||||
5-[4[[2-Butyl-4-chloro-5-[[1-methyl)oxy]methyl-1H-imidazol-1-yl]-methyl-biphenyl-2-yl]-1H-tetrazole (0 suppliers) | |||||||||
5-[4’-Carboxy-(1,1’-biphenyl)-2-yl]-2-triphenylmethyltetrazole (2 suppliers)![]() Synonyms: 5-[4 inverted exclamation mark -Carboxy-(1,1 inverted exclamation mark -biphenyl)-2-yl]-2-triphenylmethyltetrazole
InChIKey: BNXRLUDAOCEHAV-UHFFFAOYSA-N | 1797134-81-6 | ||||||||
5-[4’-(BROMOMETHYL)-(1,1-BIPHENYL)-2-YL]-1-(TRIPHENYLMETHYL)TETRAZOLE (1 supplier) | |||||||||
5-[4’-BROMOMETHYL-(1,1’-BIPHENYL)-2-YL]-2-TRIPHENYLMETHYLTETRAZOLE-D4 (1 supplier) | |||||||||
5-[5,5-DIMETHYL-3-[(3-METHYL-(3H)-BENZOTHIAZOL-2-YLIDENE)METHYL]CYCLOHEX-2-EN-1-YLIDENE]-3-ETHYL-2-THIOXOTHIAZOLIDIN-4-ONE (2 suppliers)![]() Synonyms: EINECS 280-799-2, 5-(5,5-Dimethyl-3-((3-methyl-(3H)-benzothiazol-2-ylidene)methyl)cyclohex-2-en-1-ylidene)-3-ethyl-2-thioxothiazolidin-4-one
InChIKey: BKRUMFOCKLOKJK-ILUNCUQESA-N | 83783-65-7 | ||||||||
5-[5,5-DIMETHYL-3-[(3-METHYL-(3H)-BENZOXAZOL-2-YLIDENE)METHYL]CYCLOHEX-2-EN-1-YLIDENE]-3-ETHYL-2-THIOXOTHIAZOLIDIN-4-ONE (2 suppliers)![]() Synonyms: EINECS 302-516-4, 5-(5,5-Dimethyl-3-((3-methyl-(3H)-benzoxazol-2-ylidene)methyl)cyclohex-2-en-1-ylidene)-3-ethyl-2-thioxothiazolidin-4-one
InChIKey: YRWDBTIUBCEIOC-ILUNCUQESA-N | 94109-77-0 | ||||||||
5-[5,6-DIMETHYL-1-(4-METHYLBENZYL)-1H-1,3-BENZIMIDAZOL-2-YL]-2(1H)-PYRIDINONE (1 supplier)![]() Synonyms: 5-[5,6-dimethyl-1-(4-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone, 5-[5,6-dimethyl-1-[(4-methylphenyl)methyl]benzimidazol-2-yl]-1H-pyridin-2-one, Oprea1_119519, ZINC3051065, AKOS005080283, 12J-343S, 5-{5,6-dimethyl-1-[(4-methylphenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one
InChIKey: JYVQVBVNZSQPSZ-UHFFFAOYSA-N | 400077-31-8 | ||||||||
5-[5-({[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO}METHYL)-4,5-DIHYDRO-3-ISOXAZOLYL]-4-METHYL-4H-1,2,4-TRIAZOLE-3-TH (2 suppliers)![]() Synonyms: AKOS005090103, 5-[5-({[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}methyl)-4,5-dihydro-3-isoxazolyl]-4-methyl-4H-1,2,4-triazole-3-thiol, 4H-921, 5-[5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-4,5-dihydro-1,2-oxazol-3-yl]-4-methyl-4H-1,2,4-triazole-3-thiol
InChIKey: CXLDVJNTHSDTMQ-UHFFFAOYSA-N | 400082-28-2 | ||||||||
5-[5-({[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO}METHYL)-4,5-DIHYDRO-3-ISOXAZOLYL]-5-METHYL-2-PHENYL-1,2,4-TRIAZOL (1 supplier)![]() Synonyms: 5-[5-[[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]methyl]-4,5-dihydro-1,2-oxazol-3-yl]-5-methyl-2-phenyl-1,2,4-triazolidin-3-one, 5-[5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-4,5-dihydro-1,2-oxazol-3-yl]-5-methyl-2-phenyl-1,2,4-triazolidin-3-one, SCHEMBL14049937, AKOS005089953, 5-[5-({[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}methyl)-4,5-dihydro-3-isoxazolyl]-5-methyl-2-phenyl-1,2,4-triazolan-3-one, 4H-957
InChIKey: NJLXIYHCNXUEGU-UHFFFAOYSA-N | 338422-66-5 | ||||||||
5-[5-(1,3-DIETHYL-1,2,3,4-TETRAHYDRO-6-HYDROXY-2,4-DIOXO-PYRIMIDIN-5-YL)PENTA-2,4-DIENYLIDENE]-1,3-DIETHYLBARBITURIC ACID (4 suppliers)![]() Synonyms: EINECS 259-165-4, CID11970516, 5-(5-(1,3-Diethyl-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxo-5-pyrimidinyl)penta-2,4-dienylidene)-1,3-diethylbarbituric acid
InChIKey: KOFZFWFIYXNDHR-WGDLNXRISA-N | 54444-01-8 | ||||||||
5-[5-(1,3-diethyl-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-yl)penta-2,4-dienylidene]-1,3-diethyl-2-sulfanylidene-1,3-diazinane-4,6-dione (3 suppliers)![]() Synonyms: 24765-31-9, EINECS 246-450-3, AC1L3LNS, 5,5'-(Penta-1,3-dien-1-yl-5-ylidene)bis(1,3-diethyl-2-thiobarbituric) acid, 4,6(1H,5H)-Pyrimidinedione, 5-(5-(1,3-diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2,4-pentadien-1-ylidene)-1,3-diethyldihydro-2-thioxo-, 4,6(1H,5H)-Pyrimidinedione, 5-(5-(1,3-diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2,4-pentadienylidene)-1,3-diethyldihydro-2-thioxo-, 680232-97-7
InChIKey: CDNUBETVVAAMOZ-UHFFFAOYSA-N | 207502-05-4 | ||||||||
5-[5-(1,3-dioxolan-2-yl)-2-pyridinyl]-7-isopropoxy-4-propyl-1,3-b Enzoxazol-2-amine (1 supplier)![]() Synonyms: KB-196026, 5-(5-(1,3-dioxolan-2-yl)pyridin-2-yl)-7-isopropoxy-n-propylbenzo[d]oxazol-2-amine
InChIKey: IGBVPTPNDAQXGW-UHFFFAOYSA-N | 1142188-53-1 | ||||||||
5-[5-(1,3-dioxolan-2-yl)-2-pyridinyl]-n2-propyl-1,3-benzoxazole-2,7-diamine (1 supplier)![]() Synonyms: AGN-PC-07HB93, ZINC31776876, KB-196028, 5-(5-(1,3-dioxolan-2-yl)pyridin-2-yl)-n2-propylbenzo[d]oxazole-2,7-diamine, 5-[5-(1,3-dioxolan-2-yl)pyridin-2-yl]-2-N-propyl-1,3-benzoxazole-2,7-diamine
InChIKey: NIHYIZCOQSOTDD-UHFFFAOYSA-N | 1142188-50-8 | ||||||||
5-[5-(2,4,6-trioxo-1,3-diazinan-5-yl)penta-2,4-dienylidene]-1,3-diazinane-2,4,6-trione (2 suppliers)![]() Synonyms: Pentamethinedibarbituric acid, BRN 0343925, 5,5'-(1,3-Pentadien-1-yl-5-ylidene)dibarbituric acid, Barbituric acid, 5,5'-(1,3-pentadien-1-yl-5-ylidene)di-, AC1O1BDD, 63811-39-2, LS-24645, 4-26-00-02701 (Beilstein Handbook Reference), 5-[(2E,4E)-5-(2,4,6-trioxo-1,3-diazinan-5-yl)penta-2,4-dienylidene]-1,3-diazinane-2,4,6-trione
InChIKey: CTSQFCOACUPEPW-ZPUQHVIOSA-N | 26134-70-3 | ||||||||
5-[5-(2-METHYL-1,3-THIAZOL-4-YL)ISOXAZOL-3-YL]-1,3,4-OXADIAZOL-2(3H)-ONE (1 supplier) | |||||||||
5-[5-(2-METHYL-1,3-THIAZOL-4-YL)ISOXAZOL-3-YL]-1,3,4-OXADIAZOL-2(3H)-ONE, 97% (1 supplier) | |||||||||
5-[5-(2-Thienyl)-2-thienyl]thiophene-2-carbaldehyde (14 suppliers)![]() Synonyms: 2,2':5',2''-Terthiophene-5-carboxaldehyde, AG-G-90429, 5-Formyl-2,2':5',2''-terthiophene, 5-(5-thiophen-2-ylthiophen-2-yl)thiophene-2-carbaldehyde, 5-[5-(2-THIENYL)-2-THIENYL]THIOPHENE-2-CARBALDEHYDE, ACMC-209oqz, .alpha.-T CHO deriv., 2-Formyl-alpha-terthienyl, 2-Formyl-alpha-terthiophene, AC1L9RU4, CHEMBL91933, CTK5D7997, CHEBI:246440, MolPort-000-146-401, 5-Formyl-2,2:5,2-terthiophene, SEW04053, ANW-36345, ZINC00009880, AKOS015856727, KB-196496
InChIKey: PMPDDPJYARBNGV-UHFFFAOYSA-N | 7342-41-8 | ||||||||
5-[5-(3,5-Dicarboxyphenyl)-8-quinolinyl]-1,3-benzenedicarboxylic acid (1 supplier) | 1808928-82-6 | ||||||||
5-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-isoxazol-3-yl]-2-fluoro-phenylamine (1 supplier) | 1071927-83-7 | ||||||||
5-[5-(3-nitrophenoxy)-1,3-dioxo-isoindol-2-yl]benzene-1,3-dicarboxylic acid (2 suppliers)![]() Synonyms: STK010162, BAS 00332794, CBMicro_014889, Oprea1_228597, Oprea1_583433, AC1M4E64, CHEMBL603414, CTK1H0404, MolPort-001-024-867, SMSF0005081, AKOS000638328, CB13747, MCULE-7915730516, BIM-0014746.P001, 5-[5-(3-Nitro-phenoxy)-1,3-dioxo-1,3-dihydro-isoindol-2-yl]-isophthalic acid, 5-[5-(3-nitrophenoxy)-1,3-dioxoisoindol-2-yl]benzene-1,3-dicarboxylic acid, 5-[5-(3-nitrophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]benzene-1,3-dicarboxylic acid
InChIKey: WXVRJSMFWYUKFE-UHFFFAOYSA-N | 5233-13-6 | ||||||||
5-[5-(3-pyridinyl)-1,2,4-oxadiazol-3-yl]-2(1H)-Pyridinone (0 suppliers)![]() Synonyms: SCHEMBL1423052, MolPort-010-914-468, AKOS021974928, MCULE-8169640752, 5-(5-pyridin-3-yl-1,2,4-oxadiazol-3-yl)pyridin-2(1H)-one
InChIKey: UFCHHBZJGOIPQS-DHZHZOJOSA-N | 1033724-44-5 | ||||||||
5-[5-(3-pyridyl)-1,3,4-oxadiazol-2-yl]thiophene-2,3-dicarbonitrile (0 suppliers) | 1312423-03-2 | ||||||||
5-[5-(3-Pyridyl)-1,3,4-oxadiazol-2-yl]thiophene-3-carbonitrile (0 suppliers) | 1312422-99-3 | ||||||||
5-[5-(3-pyridyl)tetrazol-2-yl]thiophene-2-carbonitrile (0 suppliers) | 1312367-98-8 | ||||||||
5-[5-(4,5-DIACETOXY-6-ACETOXYMETHYL-3-ACETYLAMINO-TETRAHYDRO-PYRAN-2-YLOXYMETHYL)-[1,2,3]TRIAZOL-1-YL]-2-HYDROXY-BENZOIC ACID METHYL ESTER (1 supplier) | |||||||||
5-[5-(4-bromophenyl)-3-hydroxypentyl]-2-methoxyphenol (3 suppliers)![]() Synonyms: MolPort-035-685-250, AKOS022188087, AK148154, 5-(5-(4-Bromophenyl)-3-hydroxypentyl)-2-methoxyphenol
InChIKey: PASGUEVOCCSZEA-UHFFFAOYSA-N | 1391150-58-5 | ||||||||
5-[5-(5-formylthiophen-2-yl)-4-[5-(4-octoxyphenyl)-1,3,4-oxadiazol-2-yl]thiophen-2-yl]thiophene-2-carbaldehyde (1 supplier)![]() Synonyms: AGN-PC-09TQGH, 2-(2,5-di(5-Thenaldehyde)thiophen-3-yl)-5-(4-(octyloxy)phenyl)-1,3,4-oxadiazole
InChIKey: RJFZQLPZUMEPJL-UHFFFAOYSA-N | 1226811-00-2 | ||||||||
5-[5-(5-formylthiophen-2-yl)-4-methylthiophen-2-yl]thiophene-2-carbaldehyde (1 supplier)![]() Synonyms: AGN-PC-09TQGJ, 2,5- di(5-Thenaldehyde)-3-methylthiophene, [2,2':5',2''-Terthiophene]-5,5''-dicarboxaldehyde, 3'-methyl-
InChIKey: HLFNNFZFCMEUDM-UHFFFAOYSA-N | 149703-88-8 | ||||||||
5-[5-(5-FORMYLTHIOPHEN-2-YL)THIOPHEN-2-YL]THIOPHENE-2-CARBALDEHYDE (1 supplier) | |||||||||
5-[5-(5-methyl-3-pyridyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbonitrile (0 suppliers) | 1312423-06-5 | ||||||||
5-[5-(6-amino-5-cyano-3-methyl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)furan-2-yl]-2-chlorobenzoic Acid (2 suppliers)![]() Synonyms: AC1NQLW5, 5-[5-(6-amino-5-cyano-3-methyl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)furan-2-yl]-2-chlorobenzoic acid
InChIKey: WXJMWJQAZIFPRV-UHFFFAOYSA-N | 5360-19-0 | ||||||||
5-[5-(6-fluoro-3-pyridyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbonitrile (0 suppliers) | 1312423-08-7 | ||||||||
5-[5-(6-methoxy-3-pyridyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbonitrile (0 suppliers) | 1312423-09-8 | ||||||||
5-[5-(6-methyl-3-pyridyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbonitrile (0 suppliers) | 1312423-07-6 | ||||||||
5-[5-(ALLYLSULFANYL)-1,3,4-OXADIAZOL-2-YL]-1-BENZYL-2(1H)-PYRIDINONE (4 suppliers)![]() Synonyms: 5-[5-(allylsulfanyl)-1,3,4-oxadiazol-2-yl]-1-benzyl-2(1H)-pyridinone, 1-benzyl-5-(5-prop-2-enylsulfanyl-1,3,4-oxadiazol-2-yl)pyridin-2-one, 1-benzyl-5-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-oxadiazol-2-yl]-1,2-dihydropyridin-2-one, ZINC3052075, AKOS005077116, MCULE-1861682479, 11E-310S
InChIKey: FJZRLYDRSYSAQM-UHFFFAOYSA-N | 477852-95-2 | ||||||||
5-[5-(ALLYLSULFANYL)-4-METHYL-4H-1,2,4-TRIAZOL-3-YL]-1-METHYL-3-PHENYL-1H-THIENO[2,3-C]PYRAZOLE (1 supplier)![]() Synonyms: 5-[5-(allylsulfanyl)-4-methyl-4H-1,2,4-triazol-3-yl]-1-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole, MLS000327045, 1-methyl-5-(4-methyl-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl)-3-phenylthieno[2,3-c]pyrazole, SMR000179590, CDS1_001547, Bionet1_004091, DivK1c_002587, CHEMBL1537075, BDBM56477, cid_5162203, HMS580I13, HMS2305J04, AKOS005100961, 7M-610S, 5-[5-(allylthio)-4-methyl-1,2,4-triazol-3-yl]-1-methyl-3-phenyl-thieno[2,3-c]pyrazole, 1-methyl-5-(4-methyl-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl)-3-phenyl-thieno[2,3-c]pyrazole, 1-methyl-5-[4-methyl-5-(prop-2-enylthio)-1,2,4-triazol-3-yl]-3-phenylthieno[2,3-c]pyrazole, 4-methyl-3-{1-methyl-3-phenyl-1H-thieno[2,3-c]pyrazol-5-yl}-5-(prop-2-en-1-ylsulfanyl)-4H-1,2,4-triazole
InChIKey: IFYKGIQCQLTSLI-UHFFFAOYSA-N | 478067-16-2 | ||||||||
5-[5-(aminomethyl)-1,2,4-oxadiazol-3-yl]pyridin-2-ol hydrochloride (1 supplier) | 2034154-11-3 | ||||||||
5-[5-(Butyrylamino)-2-chloroanilino]-5-oxopentanoic acid (2 suppliers) | |||||||||
5-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]-2-thiophenesulfonyl chloride (5 suppliers)![]() Synonyms: 5-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]thiophene-2-sulfonyl Chloride, 5-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-2-thiophenesulphonyl chloride, 5-(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)thiophene-2-sulfonyl chloride, AC1MCW3V, CTK1D5459, AG-C-05604, MO00133, QC-8244, KB-196497, FT-0619908, 5-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-2-thiophenesulfonyl chloride
InChIKey: SBJSVTQEOYREFW-UHFFFAOYSA-N | 423768-39-2 | ||||||||
5-[5-(CHLOROMETHYL)-1,3,4-OXADIAZOL-2-YL]-2-(3-CHLOROPHENYL)-4-METHOX Y-PYRAZOL-3-YL]-(4-NITROPHENYL)DIAZENE (3 suppliers)![]() Synonyms: CID3075166, CID 3075166, LS-99099, 1,3,4-Oxadiazole, 2-(chloromethyl)-5-(1-(3-chlorophenyl)-4-methoxy-5-((4-nitrophenyl)azo)-1H-pyrazol-3-yl)-
InChIKey: GFNIMJBHZLTNCT-UHFFFAOYSA-N | 172701-69-8 | ||||||||
5-[5-(CHLOROMETHYL)-1,3,4-OXADIAZOL-2-YL]-2-(3-CHLOROPHENYL)-4-METHOX Y-PYRAZOL-3-YL]-PHENYL-DIAZENE (3 suppliers)![]() Synonyms: CID3075165, LS-99100, 2-(Chloromethyl)-5-(1-(3-chlorophenyl)-4-methoxy-5-phenylazo)-1H-pyrazol-3-yl-1,3,4-oxadiazole, 1,3,4-Oxadiazole, 2-(chloromethyl)-5-(1-(3-chlorophenyl)-4-methoxy-5-(phenylazo)-1H-pyrazol-3-yl)-
InChIKey: GYUOGSSWFDOLBM-UHFFFAOYSA-N | 172701-68-7 | ||||||||
5-[5-(Chloromethyl)furan-2-yl]-1,3,4-oxadiazole-2-carboxylic acid (1 supplier) | 2060060-50-4 |