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Shanghai Up-Fluorochem Co., Ltd.

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Contact: Joe Zou - Sales Manager
Web: http://upfluorochem.com
E-Mail:
Address: T2-1623, Zhonggeng Global Creative Center Lane 166, Minhong Road, Minhang District, Shanghai 202155, China
Phone: +86-(0)-18721967067 | Map/Directions >>

Profile: Shanghai Up-Fluorochem Co., Ltd. specializes in providing fluorine-containing pharmaceuticals, pesticides & intermediates, fluorine-containing materials & intermediates, organic fluorine-containing blocks and catalysts. Our fluorinated inhibitors include cobimetinib, navitoclax, almorexant hydrochloride, afatinib, and capecitabine. We also offer voxilaprevir, siponimod, and atabecestat.

9 Products/Chemicals (Click for related suppliers)  
• ABT-263
IUPAC Name: 4-[4-[[2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide | CAS Registry Number: 923564-51-6
Synonyms: ABT 263, CHEBI:608147, 1000696-69-4, 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({4-({(1R)-3-morpholin-4-yl-1-[(phenylsulfanyl)methyl]propyl}amino)-3-[(trifluoromethyl)sulfonyl]phenyl}sulfonyl)benzamide, Benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((4-(((1R)-3-(4-morpholinyl)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)-

Molecular Formula: C47H55ClF3N5O6S3Molecular Weight: 974.612710 [g/mol]
H-Bond Donor: 2H-Bond Acceptor: 13

InChIKey: JLYAXFNOILIKPP-KXQOOQHDSA-N

• Almorexant HCL
IUPAC Name: (2R)-2-[(1S)-6,7-dimethoxy-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-3,4-dihydro-1H-isoquinolin-2-yl]-N-methyl-2-phenylacetamide;hydrochloride | CAS Registry Number: 913358-93-7
Synonyms: Almorexant hydrochloride, ACT078573 hydrochloride, ACT 078573 hydrochloride, (R)-2-((S)-6,7-Dimethoxy-1-(4-(trifluoromethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide hydrochloride, 871224-63-4, Almorexant HCl, SCHEMBL1935015, MolPort-035-395-893, HY-10805A, AKOS022180392, CS-2485, AK-59719, S2160,913358-93-7

Molecular Formula: C29H32ClF3N2O3Molecular Weight: 549.024190 [g/mol]
H-Bond Donor: 2H-Bond Acceptor: 7

InChIKey: BYGBTDRDPBJUBB-LHIMUUITSA-N

• AZD 1480
IUPAC Name: 5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine | CAS Registry Number: 935666-88-9
Synonyms: AZD1480, AZD-1480, (S)-5-chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine, 935666-88-9 , AZD 1480, AZD1480, AZD 1480, S2162_Selleck, 2xa4, UNII-KL2Z2TLF01, SureCN3345019, cc-358, QCR-23, CHEMBL1231124, CHEBI:793474, MolPort-016-633-291, BCPP000361, 5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine, ABP000832, BCP9000361, AZD1480-Supplied by Selleck Chemicals, NCGC00242486-01

Molecular Formula: C14H14ClFN8Molecular Weight: 348.765963 [g/mol]
H-Bond Donor: 3H-Bond Acceptor: 8

InChIKey: PDOQBOJDRPLBQU-QMMMGPOBSA-N

• BAF312 (Siponimod)
IUPAC Name: 1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid | CAS Registry Number: 1230487-00-9
Synonyms: UNII-RR6P8L282I, Siponimod, CHEMBL2336071, Siponimod [INN], BAF-312, 1-((4-((1E)-1-(((4-Cyclohexyl- 3-(trifluoromethyl)phenyl)methoxy)imino)ethyl)- 2-ethylphenyl)methyl)azetidine-3-carboxylic acid, Siponimod [WHO-DD], SCHEMBL641699, BAF312, RR6P8L282I, 1230487-85-0, 3-Azetidinecarboxylic acid, 1-((4-((1E)-1-(((4-cyclohexyl-3-(trifluoromethyl)phenyl)methoxy)imino)ethyl)-2-ethylphenyl)methyl)-

Molecular Formula: C29H35F3N2O3Molecular Weight: 516.595010 [g/mol]
H-Bond Donor: 1H-Bond Acceptor: 8

InChIKey: KIHYPELVXPAIDH-HNSNBQBZSA-N

• Capecitabine
IUPAC Name: pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate | CAS Registry Number: 154361-50-9
Synonyms: Xeloda, CAPECITABINE, Capecitabine [USAN], Xeloda (TN), Capecitabine (JAN/USAN/INN), C15H22FN3O6, Ro 09-1978, DB01101, Ro-09-1978, LS-59070, N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine, Ro 09-1978/000, R-340, 5'-Deoxy-5-fluoro-N-((pentyloxy)carbonyl)cytidine, C12650, D01223, C110904, Cytidine, 5'-deoxy-5-fluoro-N-((pentyloxy)carbonyl)-, Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Carbamic acid, (1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, pentyl ester

Molecular Formula: C15H22FN3O6Molecular Weight: 359.350083 [g/mol]
H-Bond Donor: 3H-Bond Acceptor: 7

InChIKey: GAGWJHPBXLXJQN-UORFTKCHSA-N

• N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
IUPAC Name: (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide | CAS Registry Number: 439081-18-2
Synonyms: Tovok, BIBW-2992, BIBW 2992, CID10184653, CID 10184653, 2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-, 915958-11-1

Molecular Formula: C24H25ClFN5O3Molecular Weight: 485.938403 [g/mol]
H-Bond Donor: 2H-Bond Acceptor: 8

InChIKey: ULXXDDBFHOBEHA-CWDCEQMOSA-N

• Voxilaprevir
Synonyms: UNII-0570F37359, GS-9857, 0570F37359, Voxilaprevir [USAN:INN], Voxilaprevir (USAN/INN), SCHEMBL15412621, AKOS032946110, DB12026, D10899, 1929654-80-7

Molecular Formula: C40H52F4N6O9SMolecular Weight: 868.943 [g/mol]
H-Bond Donor: 3H-Bond Acceptor: 15

InChIKey: MZBLZLWXUBZHSL-FZNJKFJKSA-N

• XL-518
IUPAC Name: [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone | CAS Registry Number: 934660-93-2
Synonyms: Cobimetinib, XL518, GDC 0973, GDC-0973, XL 518, CHEMBL2146883, GDC0973, [3,4-Bis(Fluoranyl)-2-[(2-Fluoranyl-4-Iodanyl-Phenyl)amino]phenyl]-[3-Oxidanyl-3-[(2s)-Piperidin-2-Yl]azetidin-1-Yl]methanone, EUI, Cobimetinib [USAN], Cobimetinib (USAN/INN), SureCN189565, UNII-ER29L26N1X, cc-456, QCR-87, Xl-518, BCP9000716, CS-0521, RG 7420, HY-13064

Molecular Formula: C21H21F3IN3O2Molecular Weight: 531.310020 [g/mol]
H-Bond Donor: 3H-Bond Acceptor: 7

InChIKey: BSMCAPRUBJMWDF-KRWDZBQOSA-N

• Zirconium Hexafluoroacetonylacetonate
IUPAC Name: 1,1,1,5,5,5-hexafluoropentane-2,4-dione; zirconium | CAS Registry Number: 19530-02-0
Synonyms: NSC177688

Molecular Formula: C20H8F24O8ZrMolecular Weight: 923.458397 [g/mol]
H-Bond Donor: 0H-Bond Acceptor: 32

InChIKey: IUYDVDKMSYOVMO-UHFFFAOYSA-N


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