Profile: Shanghai Sun-shine Chemical technology Co., Ltd specializes in custom synthesis of organic compounds and projects involving contract researches. ABT-100 is an orally bioavailable farnesyltransferase inhibitor. Arbidol is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane. AVN944 is an orally available, synthetic small molecule with potential antineoplastic activity, which inhibits inosine monosphosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis of guanosine triphosphate (GTP), a purine molecule required for DNA and RNA synthesis. Inhibition of IMPDH deprives cancer cells of GTP, resulting in disruption of DNA and RNA synthesis, inhibition of cell proliferation, and the induction of apoptosis.
11 Products/Chemicals (Click for related suppliers)
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• ABT 100
IUPAC Name: 4-[(2S)-2-(4-cyanophenyl)-2-hydroxy-2-(3-methylimidazol-4-yl)ethoxy]-3-[4-(trifluoromethoxy)phenyl]benzonitrile | CAS Registry Number: 450839-40-4 Synonyms: ABT100, ABT-100, CID6451154, A-409100
InChIKey: HEUVRFNVTLGKMZ-SANMLTNESA-N | ||||||||
• AVN-944
IUPAC Name: [(2R)-1-cyanobutan-2-yl] N-[(1S)-1-[3-[[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoylamino]phenyl]ethyl]carbamate | CAS Registry Number: 297730-17-7 Synonyms: UNII-I3NPL1V48Q, AVN944, AVN 944, NCGC00345803-01, Carbamic acid, ((1S)-1-(3-((((3-methoxy-4-(5- oxazolyl)phenyl)amino)carbonyl)amino)phenyl)ethyl)-, (1R)-1-(cyanomethyl)propyl ester
InChIKey: GYCPCOJTCINIFZ-OXJNMPFZSA-N | ||||||||
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