Hangzhou Hetd Pharm & Chem Co., Ltd.

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Profile: Hangzhou Hetd Pharm & Chem Co., Ltd. specializes in APIs and pharmaceutical intermediates. We provide contract manufacturing, customer research and manufacturing service. Our main products are anastrozole, letrozole, ezetimibe, zoledronic acid, ibandronate sodium, pacilitaxel, docetaxel, rubitecan, azasetron HCl, palonosetron HCl and bicalutamide.

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IUPAC Name: 1-[(2R,4S,5R)-4-chloro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione | CAS Registry Number: 25526-94-7
Synonyms: 3'-Chloro-3'-deoxythymidine, Thymidine, 3'-chloro-3'-deoxy-, 3'-Cl-ddT, AC1L2HPG, AC1Q69E3, CHEMBL1098010, CTK4F5976, 3'-Chloro-2',3'-dideoxythymidine, AR-1F2564, AG-J-03881, Thymidine,3'-chloro-3'-deoxy- (8CI,9CI), 1-[(2R,4S,5R)-4-chloro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione, 1-((2S,4R,5S)-4-chloro-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;

Molecular Formula:	C₁₀H₁₃ClN₂O₄	Molecular Weight:	260.674220 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	4

InChIKey: KQVJDKGDGLWBQT-XLPZGREQSA-N

• 4-O-Demethyl Griseofulvin

IUPAC Name: (2S,5'R)-7-chloro-4-hydroxy-3',6-dimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione | CAS Registry Number: 5128-41-6
Synonyms: 4-Desmethylgriseofulvin, CHEMBL1612, FT-0665720, (1'S,6'R)-7-Chloro-4-hydroxy-2',6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, (1'S-trans)- 7-Chloro-4-hydroxy-2',6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione

Molecular Formula:	C₁₆H₁₅ClO₆	Molecular Weight:	338.739700 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	6

InChIKey: KTICLSBYPHKDMM-QZTNRIJFSA-N

• (S,R)-Palonosetron Hydrochloride

IUPAC Name: (3aS)-2-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride | CAS Registry Number: 135729-76-9
Synonyms: Palonosetron hydrochloride, SureCN4054459, Bio-0138, CHEMBL545717, 135729-75-8, H672, (3aS)-2-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride

Molecular Formula:	C₁₉H₂₅ClN₂O	Molecular Weight:	332.867600 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	2

InChIKey: OLDRWYVIKMSFFB-KALLACGZSA-N

• 4-UREIDOETODOLAC

IUPAC Name: ethyl 2-[4-(carbamoylamino)-8-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetate | CAS Registry Number: 111478-85-4
Synonyms: 4-Ureidoetodolac, CID194906, Pyrano(3,4-b)indole-1-acetic acid, 4-((aminocarbonyl)amino)-1,8-diethyl-1,3,4,9-tetrahydro-

Molecular Formula:	C₁₈H₂₃N₃O₄	Molecular Weight:	345.392920 [g/mol]
H-Bond Donor:	3	H-Bond Acceptor:	4

InChIKey: JGZSZMJCKHJAKQ-UHFFFAOYSA-N

• (S)-Lercanidipine-d3 Hydrochloride

IUPAC Name: 5-O-[1-[3,3-diphenylpropyl(trideuteriomethyl)amino]-2-methylpropan-2-yl] 3-O-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride

Molecular Formula:	C₃₆H₄₂ClN₃O₆	Molecular Weight:	651.206665 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	8

InChIKey: WMFYOYKPJLRMJI-RFTUCFSWSA-N

• (R)-Lercanidipine-d3 Hydrochloride

IUPAC Name: 5-O-[1-[3,3-diphenylpropyl(trideuteriomethyl)amino]-2-methylpropan-2-yl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride

Molecular Formula:	C₃₆H₄₂ClN₃O₆	Molecular Weight:	651.206665 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	8

InChIKey: WMFYOYKPJLRMJI-UUOWBLICSA-N

• 6-Amino-5,6,7,8-Tetrahydronaphthalene-2-Carbonitrile

IUPAC Name: (6S)-6-amino-5,6,7,8-tetrahydronaphthalene-2-carbonitrile | CAS Registry Number: 882423-68-9
Synonyms: SCHEMBL2724775, PONGXMDLEGURRQ-NSHDSACASA-N, ZINC16082943, (6S)-6-amino-5,6,7,8-tetrahydronaphthalene-2-carbonitrile, 2-Naphthalenecarbonitrile, 6-amino-5,6,7,8-tetrahydro-, (6S)-

Molecular Formula:	C₁₁H₁₂N₂	Molecular Weight:	172.231 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	2

InChIKey: PONGXMDLEGURRQ-NSHDSACASA-N

• 4'-O-Demethyl Griseofulvin

IUPAC Name: (2S,5'R)-7-chloro-3'-hydroxy-4,6-dimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione | CAS Registry Number: 1158186-19-6
Synonyms: CHEMBL492110, MolPort-005-944-041, NP-003090, (1'S,6'R)-7-Chloro-4'-hydroxy-4,6-dimethoxy-6'-methyl-spiro[benzofuran-2(3H),1'-[3]cyclohexene]-2',3-dione

Molecular Formula:	C₁₆H₁₅ClO₆	Molecular Weight:	338.739700 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	6

InChIKey: KUTVEHNZHKAAAO-QZTNRIJFSA-N

• 3S, 5S enantiomer of Atorvastatin Calcium

Synonyms: 2-(4-bromo-2-nitrophenyl)acetic acid, 6127-11-3, 4-Bromo-2-nitrophenylacetic acid, (4-bromo-2-nitrophenyl)acetic acid, (4-BROMO-2-NITRO-PHENYL)-ACETIC ACID, Benzeneacetic acid,4-bromo-2-nitro-, NSC115142, AC1L6QIV, ACMC-1BAE0, AC1Q25N7, SCHEMBL1224216, CTK5B2968, LBZPHZBNFDOCCR-UHFFFAOYSA-N, MolPort-001-769-252, 4-bromo-2-nitro-phenylacetic acid, KST-1A0202, ANW-14017, AR-1A5599, FC1044, OR5592

Molecular Formula:	C₈H₆BrNO₄	Molecular Weight:	260.041540 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	4

InChIKey: LBZPHZBNFDOCCR-UHFFFAOYSA-N

• 7-Hydroxy Risperidone-d4

IUPAC Name: 7-hydroxy-2-methyl-3-[1,1,2,2-tetradeuterio-2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one | CAS Registry Number: 1215454-04-8
Synonyms: R 79242-d4, -[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-d4]-6,7,8,9-tetrahydro-7-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Molecular Formula:	C₂₃H₂₇FN₄O₃	Molecular Weight:	430.508530 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	7

InChIKey: ABWPQNZPAOAQSG-ZUPNMEAQSA-N

• 4-(2,4-Difluorobenzoyl Oxime)-Piridine Hcl

IUPAC Name: (2,4-difluorophenyl)-piperidin-4-ylmethanone;hydrochloride | CAS Registry Number: 106266-04-0
Synonyms: 4-(2,4-Difluorobenzoyl)piperidine hydrochloride, 4-(2,4-difluorobenzoyl)piperidine hcl, 4-(2,4-difluorobenzoyl)-piperidine hydrochloride, SBB063294, 4-(2,4-Difluorobenzoyl)-piperidinehydrochloride, (2,4-Difluorophenyl)-4-piperidinyl-methanone HCl, PubChem16202, ACMC-1BVIM, SureCN1836446, Jsp000572, CTK8A9124, MolPort-003-986-207, ACT04271, ANW-15325, AKOS015888702, AC-1637, LS40079, RP29316, AK-30624, H554

Molecular Formula:	C₁₂H₁₄ClF₂NO	Molecular Weight:	261.695466 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	4

InChIKey: QPJONRGTWKXJLG-UHFFFAOYSA-N

• 4-OXO ETODOLAC

IUPAC Name: 2-(1,8-diethyl-4-oxo-9H-pyrano[3,4-b]indol-1-yl)acetic acid | CAS Registry Number: 111478-86-5
Synonyms: Pyrano[3,4-b]indole-1-aceticacid, 1,8-diethyl-1,3,4,9-tetrahydro-4-oxo-, 4-Oxo Etodolac, ACMC-20eilr, SureCN8542450, AGN-PC-005M3C, CHEMBL296550, CTK0H2843, AG-D-29916, FT-0673370, 1,8-Diethyl-4-oxo-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid, Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-4-oxo-, 1,8-Diethyl-4-oxo-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid;4-Oxo Etodolac;1,8-Diethyl-4-oxo-1,3,4,9-tetrahydro-pyrano[3,4-A'A|Afas]indole-1-acetic Acid

Molecular Formula:	C₁₇H₁₉NO₄	Molecular Weight:	301.337060 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	4

InChIKey: HNWLARFJUBQIQT-UHFFFAOYSA-N

• (R,S)-Palonosetron Hydrochloride

IUPAC Name: (3aR)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride | CAS Registry Number: 135755-51-0
Synonyms: Aloxi, Palonosetron hydrochloride, Palonosetron Hydrochloride [USAN], 1H-Benz(de)isoquinolin-1-one, 2-(3S)-1-azabicyclo(2.2.2)oct-3-yl-2,3,3a,4,5,6-hexahydro-, monohydrochloride, (3aS)-, SureCN182479, UNII-23310D4I19, AC1L4373, LS-186534, FT-0600824, (3aR)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride, (3aR)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one hydrochloride, (3aS)-2,3,3a,4,5,6-Hexahydro-2-((3S)-3-quinuclidinyl)-1H-benz(de)isoquinolin-1-one monohydrochloride

Molecular Formula:	C₁₉H₂₅ClN₂O	Molecular Weight:	332.867600 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	2

InChIKey: OLDRWYVIKMSFFB-KPVRICSOSA-N

• 6-DESFLUORO-6-HYDROXY RISPERIDONE

IUPAC Name: 3-[1-[2-(2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-3-yl)ethyl]piperidin-4-yl]-2H-1,2-benzoxazol-6-one | CAS Registry Number: 106266-11-9
Synonyms: 6-Desfluoro-6-hydroxy Risperidone, SureCN7292287, CTK8F1073, 6,7,8,9-Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Molecular Formula:	C₂₃H₂₈N₄O₃	Molecular Weight:	408.493420 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	6

InChIKey: LCDJWMXDUIZIKO-UHFFFAOYSA-N

• (S)-9-Hydroxy Risperidone

IUPAC Name: (9S)-3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one | CAS Registry Number: 147663-01-2
Synonyms: (S)-paliperidone, NCGC00183874-01, SCHEMBL11899798, CHEBI:83805, Pharmakon1600-01502318, ZINC4214700, NSC759623, NSC-759623, AJ-48964, AB01274705-01, AB01274705_02, (9S)-3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one, (9S)-3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one

Molecular Formula:	C₂₃H₂₇FN₄O₃	Molecular Weight:	426.492 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	7

InChIKey: PMXMIIMHBWHSKN-IBGZPJMESA-N

• 8-METHYL ETODOLAC

IUPAC Name: ethyl 2-(8-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate | CAS Registry Number: 41340-19-6
Synonyms: CCRIS 5408, RAK-701, BRN 1012521, CID198230, LS-127361, 1-Ethyl-8-methyl-1,3,4,9-tetrahydropyrano(3,4-b)indole, 1-Ethyl-9-methyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid, Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1-ethyl-9-methyl-

Molecular Formula:	C₁₆H₁₉NO₃	Molecular Weight:	273.326960 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	3

InChIKey: KAQBLWDALHVJDR-UHFFFAOYSA-N

• 6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2-diyl bis(2-methylpropanoate) hydrochloride(1:1)

IUPAC Name: [6-(methylamino)-1-(2-methylpropanoyloxy)-5,6,7,8-tetrahydronaphthalen-2-yl] 2-methylpropanoate;hydrochloride | CAS Registry Number: 138531-51-8
Synonyms: Nolomirole hydrochloride, Nolomirole HCl, AC1Q3EAU, SureCN250862, AC1L55YS, CTK4C1292, CHF 1035, CHF-1035, AR-1H0036, AG-K-05593, [6-(methylamino)-1-(2-methylpropanoyloxy)-5,6,7,8-tetrahydronaphthalen-2-yl] 2-methylpropanoate hydrochloride, Propanoic acid, 2-methyl-, 5,6,7,8-tetrahydro-6-(methylamino)-1,2-naphthalenediyl ester, hydrochloride

Molecular Formula:	C₁₉H₂₈ClNO₄	Molecular Weight:	369.882920 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	5

InChIKey: TWTMQRXNAZGSCE-UHFFFAOYSA-N

• 9-Keto Risperidone

IUPAC Name: 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-7,8-dihydro-6H-pyrido[1,2-a]pyrimidine-4,9-dione | CAS Registry Number: 1189516-65-1
Synonyms: SureCN1119098, CTK8E9244, 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione

Molecular Formula:	C₂₃H₂₅FN₄O₃	Molecular Weight:	424.468003 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	7

InChIKey: AUSFXKQDZJPCTA-UHFFFAOYSA-N

• 5-AMINO-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL

IUPAC Name: 5-amino-5,6,7,8-tetrahydronaphthalen-2-ol | CAS Registry Number: 765861-94-7
Synonyms: 5-amino-5,6,7,8-tetrahydronaphthalen-2-ol, AG-H-05695, SureCN8274690, AGN-PC-0004XF, AC1Q53F9, AKOS011107810, AB43911

Molecular Formula:	C₁₀H₁₃NO	Molecular Weight:	163.216320 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	2

InChIKey: OGCNDVHUWVSJRM-UHFFFAOYSA-N

• 6-DEMETHYLGRISEOFULVIN

IUPAC Name: 7-chloro-6-hydroxy-3',4-dimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione | CAS Registry Number: 20168-88-1
Synonyms: 6-Demethylgriseofulvin, 6-Desmethylgriseofulvin, CID161302, (1'S-trans)-7-Chloro-6-hydroxy-2',4-dimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexen e)-3,4'-dione, InChI=1/C16H15ClO6/c1-7-4-8(18)5-11(22-3)16(7)15(20)12-10(21-2)6-9(19)13(17)14(12)23-16/h5-7,19H,4H2,1-3H, Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-6-hydroxy-2',4-dimethoxy-6'-methyl-, (1'S-trans)-

Molecular Formula:	C₁₆H₁₅ClO₆	Molecular Weight:	338.739700 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	6

InChIKey: SYNGDIBHUPXIQA-UHFFFAOYSA-N