GBL Hisoar Ltd.

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Profile: GBL Hisoar Ltd.specializes in developing, synthesizing, and manufacturing pharmaceutical intermediates & fine chemicals. Our active pharmaceutical ingredients include ambrisentan, plerixafor, istradefylline, raltirexed, ibutilide fumarate, gadopentetate dimeglumine and licofelone. We offer intermediates such as 1,4,8,11-tetra azacyclotetradecane, 1,4,7,10-tetra azacyclododecane, 4,6-dichloro-2-(propylthio)-5-pyrimidinamine, 1,4,7,10-tetra azacyclododecane 4HCL and 4-amino-3-chloro-5-methylphenol.

12 Products/Chemicals (Click for related suppliers)

• Active Pharmaceutical Ingredient (API)

• Azelnidipine

IUPAC Name: 3-O-[1-[di(phenyl)methyl]azetidin-3-yl] 5-O-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | CAS Registry Number: 123524-52-7
Synonyms: Calblock, Azelnidipine [INN], Calblock (TN), Azelnidipine (JAN/INN), CS 905, CS-905, C33H34N4O6, CID65948, RS-9054, NCGC00167436-01, LS-131184, D01145, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-amino-6-methyl-4-(3-nitrophenyl)-, 3-(1-(diphenylmethyl)-3-azetidinyl) 5-(1-methylethyl) ester, (+-)-, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-amino-6-methyl-4-(3-nitrophenyl)-, 3-(1-(diphenylmethyl)-3-azetidinyl)-5-(1-methylethyl) esster, (+-)-, 3,5-Pyridinedicarboxylic acid, 2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, 3-(1-(diphenylmethyl)-3-azetidinyl) 5-(1-methylethyl) ester, (+-)-, 3-(1-(Diphenylmethyl)-3-azetidinyl) 5-isopropyl (+-)-2-amino-1,4-dihydro-6-methyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate, 3-[1-(diphenylmethyl)azetidin-3-yl] 5-(1-methylethyl) 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-amino-6-methyl-4-(3-nitrophenyl)-,3-(1-(diphenylmethyl)-3-azetidinyl)-5-(1-methylethyl) esster, (+-)-, 3-(1-diphenylmethylazetidin-3-yl)-5-isopropyl-2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

Molecular Formula:	C₃₃H₃₄N₄O₆	Molecular Weight:	582.646260 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	9

InChIKey: ZKFQEACEUNWPMT-UHFFFAOYSA-N

• Darusentan

IUPAC Name: (2S)-2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-di(phenyl)propanoic acid | CAS Registry Number: 171714-84-4
Synonyms: Lu 135252, HMR-4005, LU-135252, LS-31102, LU135252, LU 127043, C107831, 2-(4,6-dimethoxypyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropionic acid, Benzenepropanoic acid, alpha-((4,6-dimethoxy-2-pyrimidinyl)oxy)-beta-methoxy-beta-phenyl-, (alphaS)-, Benzenepropanoic acid, alpha-((4,6-dimethoxy-2-pyrimidinyl)oxy)-beta-methoxy-beta-phenyl-, (S)-, (+)-(S)-2-((4,6-Dimethoxy-2-pyrimidinyl)oxy)-3-methoxy-3,3-diphenylpropionic acid, 177036-80-5

Molecular Formula:	C₂₂H₂₂N₂O₆	Molecular Weight:	410.419880 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	8

InChIKey: FEJVSJIALLTFRP-LJQANCHMSA-N

• Gadopentetate Dimeglumine

IUPAC Name: 2-[bis[2-[bis(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate; gadolinium(3+); hydron; (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol | CAS Registry Number: 86050-77-3
Synonyms: Magnevist, Resovist, Gadolinium dtpa, Dimeglumine-gadolinium-dtpa, Gadolinium-DTPA-dimeglumine, UNII-RH248G8V27, GADOPENTETATE DIMEGLUMINE, SHL 451A, HSDB 7548, Gadopentetic acid dimeglumine salt, 80529-93-7 (Parent), ZK 93035, Diethylenetriaminepentaacetic acid dimeglumine salt gadolinium chelate, Gadolinate(2-), (N,N-bis(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-))-, dihydrogen, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2)

Molecular Formula:	C₂₈H₅₄GdN₅O₂₀	Molecular Weight:	937.999860 [g/mol]
H-Bond Donor:	12	H-Bond Acceptor:	25

InChIKey: LGMLJQFQKXPRGA-VPVMAENOSA-K

• Gadopentetate monomeglumine

IUPAC Name: 2-[bis[2-[carboxylatomethyl(carboxymethyl)amino]ethyl]amino]acetate;gadolinium(3+);(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol | CAS Registry Number: 92923-57-4
Synonyms: MOLI000975, Gadopentetate Monomeglumine, AC1L9OZ1, Meglumine gadopentetate (JAN), AT-25077, D09795

Molecular Formula:	C₂₁H₃₇GdN₄O₁₅	Molecular Weight:	742.786280 [g/mol]
H-Bond Donor:	8	H-Bond Acceptor:	19

InChIKey: LZQIEMULHFPUQY-BMWGJIJESA-K

• Gadoteric Acid

IUPAC Name: gadolinium(3+); 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid | CAS Registry Number: 72573-82-1
Synonyms: Gadoteric acid, CID3085828

Molecular Formula:	C₁₆H₂₈GdN₄O₈+₃	Molecular Weight:	561.665520 [g/mol]
H-Bond Donor:	4	H-Bond Acceptor:	12

InChIKey: GFSTXYOTEVLASN-UHFFFAOYSA-N

• Gadoteridol

IUPAC Name: gadolinium(3+); 2-[4-(2-hydroxypropyl)-7,10-bis(2-oxido-2-oxoethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate | CAS Registry Number: 120066-54-8
Synonyms: Gadoteridolum, ProHance, Prohance Multipack, GADOTERIDOL, Gadolinium-HP-DO3A, Gadolinium-HP-Do 3A, Gadoteridolum [INN-Latin], GD-HP-DO 3A, UNII-0199MV609F, HSDB 7549, SQ 32692, (10-(2-Hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato)gadolinium, 1,4,7,10-Tetraazacyclododecan-1,4,7-triacetic acid, 10-(2-hydroxypropyl)-, gadolinium complex, Gadolinium, (10-(2-(hydroxy-kappaO)propyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kappaN1,kappaN4,kappaN7,kappaN10,kappaO1,kappaO4,kappaO7)-, Gadolinium, (10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-N(sup 1),N(sup 4),N(sup 7),N(sup 10),O(sup 1),O(sup 4),O(sup 7),O(sup 10))-

Molecular Formula:	C₁₇H₂₉GdN₄O₇	Molecular Weight:	558.684760 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	11

InChIKey: DPNNNPAKRZOSMO-UHFFFAOYSA-K

• Pharmaceutic Intermediates

• Pharmaceutical Intermediates

• Sodium Valproate

IUPAC Name: sodium 2-propylpentanoate | CAS Registry Number: 1069-66-5
Synonyms: Sodium valproate, Valproate sodium, Depakene, Epilim, Convulex, Eurekene, Labazene, Orfiril, Valerin, Natrium valproat, Selenica, Sodium 2-propylpentanoate, Valproic acid sodium salt, Dipropylacetate sodium, Sodium dipropylacetate, Depakene (TN), Selenica (TN), Sodium bispropylacetate, Valproic acid sodium, Valproinsaeure, natrium

Molecular Formula:	C₈H₁₅NaO₂	Molecular Weight:	166.193270 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	2

InChIKey: AEQFSUDEHCCHBT-UHFFFAOYSA-M

• Stiripentol

IUPAC Name: (E)-1-(1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol | CAS Registry Number: 49763-96-4
Synonyms: STIRIPENTOL, Stiripentolum, Estiripentol, Diacomit, Stiripentolum [INN-Latin], Estiripentol [INN-Spanish], Stiripentol (USAN/INN), Stiripentol [USAN:INN], MLS000758313, MLS001424144, BCX 2600, EINECS 256-480-9, BCX-2600, C14H18O3, BRN 1313047, CID5311454, CPD000449279, SAM001247042, SMR000449279, LS-102117

Molecular Formula:	C₁₄H₁₈O₃	Molecular Weight:	234.290920 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	3

InChIKey: IBLNKMRFIPWSOY-FNORWQNLSA-N

• Ticagrelor

IUPAC Name: (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol | CAS Registry Number: 274693-27-5
Synonyms: Brilinta, Brilique, AZD-6140, TICARGRELOR, AZD6140, CHEBI:68558, AR-C 126532XX, AZD 6140, (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol, (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-DIFLUOROPHENYL)CYCLOPROPYL]AMINO]-5-(PROPYLTHIO)-3H-1,2,3-TRIAZOLO[4,5-D]PYRIMIDIN-3-YL]-5-(2-HYDROXYETHOXY)-1,2-CYCLOPENTANEDIOL, UNII-GLH0314RVC, Possia, Brilinta (TN), (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol, Ticagrelor (USAN/INN), SureCN1979652, GLH0314RVC, cc-291, CHEMBL398435, AR-C126532XX

Molecular Formula:	C₂₃H₂₈F₂N₆O₄S	Molecular Weight:	522.568026 [g/mol]
H-Bond Donor:	4	H-Bond Acceptor:	12

InChIKey: OEKWJQXRCDYSHL-FNOIDJSQSA-N