Aptonchem Co., Ltd.

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Contact: Bob Ge
Web: http://www.aptonchem.com
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Address: 387#, Qige, Xiasha Road, Jianggan District, Hangzhou, Zhejiang 310018, China
Phone: +86-(0)-15957196741 | Fax: +86-(571)-56389107 | Map/Directions >>

Profile: Aptonchem Co., Ltd. is engaged in custom synthesis and contract manufacturing of APIs, pharmaceutical intermediates, pesticide intermediates and special chemical reagent, from gram to multi ton scale. We provide amprenavir, darunavir, fosamprenavir calcium salt, delavirdine, 3-hydroxytetrahydrofuran, 5-chlorooxindole, (s)-1-benzyl-3-pyrrolidinol, maraviroc, raltegravir, l-biopterin, prulifloxacin, atazanavir sulfate , lapatinib ditosylate, entecavir hydrate, adefovir, erlotinib, gefitinib, imatinib mesylate, nilotinib, gemcitabine hydrochloride, fludarabine phosphate, argatroban, posaconazole, sitafloxacin, fulvestrant, letrozole, masitinib, axitinib and sunitinib.

16 Products/Chemicals (Click for related suppliers)

• Amprenavir

IUPAC Name: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate | CAS Registry Number: 161814-49-9
Synonyms: amprenavir, Agenerase, Prozei, Vertex, Vertex VX478, 1hpv, Amprenavir [USAN], Agenerase (TM), Agenerase (TN), GNA & Amprenavir, HHA & Amprenavir, 1t7j, VX-478, VX 478, HSDB 7157, Amprenavir (JAN/USAN/INN), DRG-0258, C25H35N3O6S, CHEBI:40050, KVX-478

Molecular Formula:	C₂₅H₃₅N₃O₆S	Molecular Weight:	505.626900 [g/mol]
H-Bond Donor:	3	H-Bond Acceptor:	8

InChIKey: YMARZQAQMVYCKC-OEMFJLHTSA-N

• Azacyclonol Base

IUPAC Name: di(phenyl)-piperidin-4-ylmethanol | CAS Registry Number: 115-46-8
Synonyms: Azacyclonol, Frenquel, gamma-Pipradol, Prestwick_84, Azaciclonolo [DCIT], Azacyclonolum [INN-Latin], Azacyclonol [INN:BAN], Maybridge3_001033, Prestwick0_000093, Prestwick1_000093, Prestwick2_000093, Prestwick3_000093, alpha-(4-Piperidyl)benzhydrol, MER 17, Oprea1_114075, Oprea1_848733, BSPBio_000046, Diphenyl-piperidin-4-yl-methanol, MLS000558844, MLS001201777

Molecular Formula:	C₁₈H₂₁NO	Molecular Weight:	267.365440 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	2

InChIKey: ZMISODWVFHHWNR-UHFFFAOYSA-N

• Darunavir

IUPAC Name: [(3R,3aS,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate | CAS Registry Number: 206361-99-1
Synonyms: Prezista, Darunavirum, 2idw, 2ien, Darunavir [USAN], TMC-114, Darunavirum [INN-Latin], TMC114, 2f8g, 2hs1, 2hs2, Darunavir (USAN/INN), UIC-94017, TMC 114, AIDS073035, UNII-YO603Y8113, 2f80, 2f81, AIDS-073035, CID213039

Molecular Formula:	C₂₇H₃₇N₃O₇S	Molecular Weight:	547.663580 [g/mol]
H-Bond Donor:	3	H-Bond Acceptor:	9

InChIKey: CJBJHOAVZSMMDJ-HEXNFIEUSA-N

• Fosamprenavir Calcium

IUPAC Name: calcium [(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonylamino]-4-phenylbutan-2-yl] phosphate | CAS Registry Number: 226700-81-8
Synonyms: Lexiva, Fosamprenavir calcium, Telzir, Lexiva (TN), Amprenavir phosphate calcium, Fosamprenavir calcium [USAN], Fosamprenavir calcium (USAN), GW433908G, CID131535, VX-175, GW-433908G, GW-433908, LS-186584, D03835, ((3S)Oxolan-3-yloxy)-N-((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-benzyl-2-(phosphonooxy)propyl)carboxamide calcium salt, Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3S)-tetrahydro-3-furanyl) ester, calcium salt, (3S)-Tetrahydro-3-furyl ((alphaS)-alpha-((1R)-1-hydroxy-2-(N(sup 1)-isobutylsulfanilamido)ethyl)phenethyl)carbamate, calcium phosphate (ester) (1:1), Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3S)-tetrahydro-3-furanyl) ester, calcium salt (1:1)

Molecular Formula:	C₂₅H₃₄CaN₃O₉PS	Molecular Weight:	623.668921 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	11

InChIKey: PMDQGYMGQKTCSX-HQROKSDRSA-L

• Glycerol Acetonide

IUPAC Name: (2,2-dimethyl-1,3-dioxolan-4-yl)methanol | CAS Registry Number: 100-79-8
Synonyms: Solketal, Glycerolacetone, Dioxolan, Acetone glycerol, Glycerol dimethylketal, Isopropylidene glycerol, Glycerol acetonide, DIOXOLANE, D-Acetone glycerol, Acetone monoglycerol ketal, Ambap651, Glycerinisopropylidene ether, 1,2-Isopropylideneglycerin, 1,2-Isopropylideneglycerol, 2,3-Isopropylideneglycerol, Glycerol acetonide (VAN), 1,2-O-Isopropylideneglycerol, 1,2-O,O-Isopropylideneglycerin, Glycerol, 1,2-O-isopropylidene, 2,3-(Isopropylidenedioxy)propanol

Molecular Formula:	C₆H₁₂O₃	Molecular Weight:	132.157680 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	3

InChIKey: RNVYQYLELCKWAN-UHFFFAOYSA-N

• N,N'-Disuccinimidyl carbonate

IUPAC Name: bis(2,5-dioxopyrrolidin-1-yl) carbonate | CAS Registry Number: 74124-79-1
Synonyms: Di(succinimido) carbonate, N-Succinimidyl carbonate, Di(N-succinimidyl) carbonate, 225827_ALDRICH, carbonic acid disuccinimido ester, 43720_FLUKA, EINECS 277-730-3, CID676246, SBB005976, TL8006647, DSC

Molecular Formula:	C₉H₈N₂O₇	Molecular Weight:	256.169020 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	7

InChIKey: PFYXSUNOLOJMDX-UHFFFAOYSA-N

• N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-N-(2-METHYLPROPYL)-4-AMINOBENZENESULFONAMIDE

IUPAC Name: 4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide | CAS Registry Number: 169280-56-2
Synonyms: 4-AMINO-N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYLBENZENESULFONAMIDE, AG-E-18617, SureCN1051190, CTK4D3254, MolPort-019-903-994, ANW-59657, AKOS015901571, RL02179, AK-43483, KB-240238, FT-0661566, I14-14145, 4-Amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide, 4-AMINO-N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-N-ISOBUTYLBENZENE-1-SULFONAMIDE, Benzenesulfonamide,4-amino-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-(2-methylpropyl)-, [R-(R*,S*)]-;, Benzenesulfonamide,4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-

Molecular Formula:	C₂₀H₂₉N₃O₃S	Molecular Weight:	391.527560 [g/mol]
H-Bond Donor:	3	H-Bond Acceptor:	6

InChIKey: NUMJNKDUHFCFJO-VQTJNVASSA-N

• N-Phenylpiperazine

IUPAC Name: 1-phenylpiperazin-4-ium | CAS Registry Number: 92-54-6
Synonyms: ZINC00120271, CID3732046

Molecular Formula:	C₁₀H₁₅N₂+	Molecular Weight:	163.239500 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	1

InChIKey: YZTJYBJCZXZGCT-UHFFFAOYSA-O

• 1-(4-Methoxyphenyl) Piperazine 2HCl

IUPAC Name: 1-(4-methoxyphenyl)piperazine chloride | CAS Registry Number: 38869-47-5
Synonyms: EINECS 254-166-6, NSC71661, CID3084721, Piperazine, 1-(4-methoxyphenyl)-, dihydrochloride, 1-(4-Methoxyphenyl)piperazine-1,4-diylium dichloride

Molecular Formula:	C₁₁H₁₆ClN₂O-	Molecular Weight:	227.710540 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	4

InChIKey: HFJDUYKRPHHPAX-UHFFFAOYSA-M

• 5-Chlorooxindole

IUPAC Name: 5-chloro-1,3-dihydroindol-2-one | CAS Registry Number: 17630-75-0
Synonyms: 127485_ALDRICH, ALBB-006976, 5-Chloro-1,3-dihydro-2H-indol-2-one, 5-Chloro-1,3-dihydro-indol-2-one, SBB003879, ZINC00161358, Indol-2-one, 5-chloro-1,3-dihydro-, 7-Chloro-1,3-dihydro-2H-indol-2-one, 2H-Indol-2-one, 7-chloro-1,3-dihydro-, TL8001400, C-5240, SR-01000637295-1, 25369-33-9, InChI=1/C8H6ClNO/c9-6-1-2-7-5(3-6)4-8(11)10-7/h1-3H,4H2,(H,10,11

Molecular Formula:	C₈H₆ClNO	Molecular Weight:	167.592340 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	1

InChIKey: WWJLCYHYLZZXBE-UHFFFAOYSA-N

• (S)-3-Hydroxy-1-benzylpyrrolidine

IUPAC Name: (3S)-1-benzylpyrrolidin-3-ol | CAS Registry Number: 101385-90-4
Synonyms: (S)-1-Benzyl-3-pyrrolidinol, (S)-1-Benzylpyrrolidin-3-ol, (S)-1-Benzyl-3-hydroxypyrrolidine, (3S)-1-benzylpyrrolidin-3-ol, s-bhp, (S)-(-)-1-Benzyl-3-pyrrolidinol, (s)-1-benzyl-pyrrolidin-3-ol, (S)-N-Benzyl-3-hydroxypyrrolidine, (s)-1-n-benzyl-3-hydroxypyrrolidine, (s)-n-benzyl-3-pyrrolidinol, (s)-1-benzyl-pyrrolidine-3-ol, (s)-3-hydroxy-1-benzylpyrrolidine, (3s)-(-)-n-benzyl-3-pyrrolidinol, (S)-3-Hydroxy-1-benzyl-pyrrolidine, (s)-1-n-benzyl-3-hydroxypyrrolidinol, (s)-(-)-1-benzyl-3-hydroxypyrrolidine, (s)-(-)-n-benzyl 3-hydroxypyrrolidine, ST50408489, (S)-( pound inverted question mark)-1-Benzyl-3-pyrrolidinol, PubChem13097

Molecular Formula:	C₁₁H₁₅NO	Molecular Weight:	177.242900 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	2

InChIKey: YQMXOIAIYXXXEE-NSHDSACASA-N

• 1,2,3,4-Tetrahydro-1-naphthylamine

IUPAC Name: 1,2,3,4-tetrahydronaphthalen-1-amine | CAS Registry Number: 2217-40-5
Synonyms: 2-Aminotetralin, 1-Aminotetralin, Aminotetralin [Czech], Tetrahydro-beta-naphthylamine, 247820_ALDRICH, EINECS 220-973-7, 1,2,3,4-Tetrahydro-2-naphthylamine, beta-1,2,3,4-Tetrahydronaphthylamine, NSC30349, BRN 1102357, EINECS 218-712-7, NSC 30349, 1,2,3,4-Tetrahydro-1-naphthalenamine, LS-95751, 1-Naphthalenamine, 1,2,3,4-tetrahydro-, 2-Amino-1,2,3,4-tetrahydronaftalen [Czech], 2-NAPHTHYLAMINE, 1,2,3,4-TETRAHYDRO-, ST5213776, 4-12-00-02943 (Beilstein Handbook Reference), THN

Molecular Formula:	C₁₀H₁₃N	Molecular Weight:	147.216920 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	1

InChIKey: JRZGPXSSNPTNMA-UHFFFAOYSA-N

• 3-Hydroxytetrahydrofuran

IUPAC Name: (3R)-oxolan-3-ol | CAS Registry Number: 453-20-3
Synonyms: Tetrahydrofuran-3-ol, 3-Furanol, tetrahydro-, 309753_ALDRICH, NSC71875, CID641512, ZINC04716349, (R)-(−)-3-Hydroxytetrahydrofuran, InChI=1/C4H8O2/c5-4-1-2-6-3-4/h4-5H,1-3H

Molecular Formula:	C₄H₈O₂	Molecular Weight:	88.105120 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	2

InChIKey: XDPCNPCKDGQBAN-SCSAIBSYSA-N

• 2-(4-Nitrophenyl)butyric acid

IUPAC Name: 2-(4-nitrophenyl)butanoic acid | CAS Registry Number: 7463-53-8
Synonyms: 2-(p-Nitrophenyl)butyric acid, EINECS 231-256-3, alpha-Ethyl-4-nitrobenzeneacetic acid, NSC 68215, NSC 404387, NSC23310, NSC68215, NSC404387, BUTYRIC ACID, 2-(p-NITROPHENYL)-, Benzeneacetic acid, alpha-ethyl-4-nitro-, LS-48129, ST5446656, Benzeneacetic acid, alpha-ethyl-4-nitro- (9CI), 46406-87-5

Molecular Formula:	C₁₀H₁₁NO₄	Molecular Weight:	209.198640 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	4

InChIKey: XBGNOMBPRQVJSR-UHFFFAOYSA-N

• 1-Aminoindan

IUPAC Name: 2,3-dihydro-1H-inden-1-amine | CAS Registry Number: 34698-41-4
Synonyms: 1-Aminoindane, 1-Indanamine, Indan-1-ylamine, NCIOpen2_000245, A59506_ALDRICH, NSC62540, EINECS 252-158-7, SBB004212, 1H-Inden-1-amine, 2,3-dihydro-, (+-)-, 1H-Inden-1-amine, 2,3-dihydro-, (.+/-.)-, 61949-83-5, InChI=1/C9H11N/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4,9H,5-6,10H

Molecular Formula:	C₉H₁₁N	Molecular Weight:	133.190340 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	1

InChIKey: XJEVHMGJSYVQBQ-UHFFFAOYSA-N

• α-(p-Aminophenyl)butyric Acid

IUPAC Name: 2-(4-aminophenyl)butanoic acid | CAS Registry Number: 29644-97-1
Synonyms: 2-(p-Aminophenyl)butyric acid, NSC27530, OWH-BB-8812, NSC 27530, AIDS019033, AIDS025530, BUTYRIC ACID, 2-(p-AMINOPHENYL)-, AIDS-019033, AIDS-025530, CID34655, 1-alpha-(p-Aminophenyl)butyric acid, dl-alpha-(p-Aminophenyl)butyric acid, BBV-182064, LS-47833

Molecular Formula:	C₁₀H₁₃NO₂	Molecular Weight:	179.215720 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	3

InChIKey: WAPLXGPARWRGJO-UHFFFAOYSA-N